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What is anaphylaxis?
Anaphylaxis, also known as anaphylactic shock, is a very severe form of allergic reaction. Immediate and life-threatening symptoms, including breathing difficulties, can be the result of exposure to a trigger. Anaphylaxis is a serious but treatable medical condition.
When a foreign substance enters your body, your immune system mounts a defence by producing antibodies. Anaphylaxis occurs when your immune system overreacts to a trigger that would normally be harmless. When this occurs, a chemical chain reaction leads to severe allergy symptoms. These triggers are known as allergens and can include:
Nearly any food can trigger a food allergy that can develop into an anaphylactic shock. Foods that commonly trigger anaphylaxis include:
- Crustaceans (e.g., lobsters, prawns and crabs);
- Nuts (e.g., peanuts, cashews, walnuts, pecans and almonds);
- Soy products;
- Sesame products, and;
- Ants, and;
- Some prescription medications (e.g., penicillin);
- Some over-the-counter medications (e.g., aspirin), and;
- Herbal preparations.
- Anaesthetics, and;
Sometimes, despite in-depth investigations, the trigger cannot be found in some people.
Some risk factors associated with anaphylaxis may include:
History of anaphylaxis
If you have a personal history of experiencing anaphylaxis, you are at risk of having the allergic reaction again. These subsequent allergic reactions can be more serious than the first reaction. If there is a family history of anaphylaxis to a certain allergen, there is a higher risk of you developing anaphylaxis to this trigger.
Signs and symptoms
The symptoms of anaphylaxis may occur within minutes of being exposed to an allergen, with 20 minutes being the average amount of time for symptoms to appear. Some signs and symptoms can include:
- Swelling of the face (e.g., the lips or eyelids);
- Skin reactions (e.g. reddening of the skin, or hives);
- Swollen tongue;
- Swollen throat;
- Tightening of the airways;
- Hoarseness in the voice or an inability to talk;
- Wheezing or coughing;
- Nausea, vomiting or diarrhoea;
- Reduction in blood pressure;
- Dizziness, fainting or unconsciousness, and;
- Paleness and floppiness in children.
Methods for diagnosis
To diagnose anaphylaxis or to identify an allergen that is affecting you, some tests can include:
- Evaluation of medical history;
- Examination of signs and symptoms during anaphylaxis;
- Blood tests (e.g., for certain antibodies), and;
- Skin prick tests to rule out or confirm suspected triggers.
Types of treatment
Treatment of anaphylaxis can include:
As anaphylaxis is a very serious medical emergency, it is important that you call an ambulance immediately (000) and follow the medical personnel's instructions. If you have an adrenaline auto-injector (see below) and have been trained in how to use it, it is best to administer this first.
This involves an injection of adrenaline, usually into the muscle of your outer thigh, to treat the reaction.
Once your doctor identifies that you are at risk of anaphylaxis, they will prescribe you adrenaline. This comes as an auto-injectable device, commonly known as Epipen®, which is designed to deliver a precise dose of adrenaline to treat anaphylaxis. There are different dosage levels for children and adults.
To help determine the specific cause of your anaphylaxis, your doctor may refer you to see an allergy specialist. They can help you create an anaphylaxis management plan.
When severe anaphylactic shock occurs, life-threatening conditions can arise. These complications can include stopping of breathing or heart contractions. In this case, you will require cardiopulmonary resuscitation (CPR) and other emergency treatment immediately.
In some cases, children will grow out of their allergies. If you have been diagnosed with anaphylaxis caused by a certain allergen, you may be able to avoid the trigger and not experience anaphylaxis. However, it is important to carry an adrenaline auto-injector just in case you are exposed to an allergen that causes anaphylaxis.
In order to help prevent anaphylaxis, a management plan can be created. Some suggestions to consider include:
- Avoiding triggers that are known to cause anaphylaxis;
- Notifying your work colleagues and friends of your allergies and how they can help treat you in an emergency, and;
- Wearing a medical bracelet that will alert ambulance officers to your condition, if you become unconscious.
FAQ Frequently asked questions
What is anaphylaxis?
Anaphylaxis, also known as anaphylactic shock, is the most severe form of allergic reaction. Immediate and life-threatening symptoms, including breathing difficulties, can be the result of exposure to an allergen (trigger). Without prompt medical attention, anaphylaxis …
What are the symptoms of anaphylaxis?
The symptoms of anaphylaxis can occur almost immediately after exposure to an allergen. Anaphylaxis can occur within minutes: 20 minutes is the average amount of time for symptoms to appear. Symptoms can include: • Facial swelling, including swelling …
What causes anaphylaxis?
Anaphylaxis occurs when your immune system overreacts to a trigger that would be harmless for most people. Common triggers include: certain foods (e.g., nuts, shellfish), insect venom (e.g., bees or wasps) and some medications (e.g., penicillin or aspirin). Less …
Who gets anaphylaxis?
Anaphylaxis can affect anyone that has a severe allergy. Sometimes children will grow out of allergies or triggers.
How is anaphylaxis diagnosed?
Anaphylaxis can be diagnosed using a combination of different tests. These can include a doctor reviewing your medical history, examination of signs and symptoms during anaphylaxis, blood tests (e.g., for the presence of certain antibodies) and skin prick …
How is anaphylaxis treated?
If you or someone else is experiencing anaphylaxis, it is important to call an ambulance. Treatment involves an injection of adrenaline, usually given into the thigh muscle. If your doctor has identified that you are at risk of anaphylaxis, they will prescribe …
Can anaphylaxis be cured?
Anaphylaxis cannot be cured. Some children may grow out of one or more of their particular food allergies. Otherwise, avoiding known triggers is the only way to prevent anaphylaxis.
Will anaphylaxis clear on its own?
No, anaphylaxis is a very serious condition and will rarely clear on its own. It is best to call an ambulance as you will require an injection of adrenaline and sometimes other treatment.
What can be done at home to treat anaphylaxis?
If your doctor has identified that you are at risk of anaphylaxis, they will prescribe you injectable adrenaline, or adrenaline shots, for you to carry with you at all times so that you can be treated immediately if you have an anaphylactic …